Core Facilities by Category
Columbia's core facilities provide investigators with shared access to technically specialized, high-end instrumentation and services. Although these facilities are housed within specific departments or centers, they are accessible to all Columbia faculty, staff, and students.
Commonly requested facilities are grouped by category below. For a full listing of facilities, you can search for shared research facilities on our website.
New Facilities and Resources
New core facilities and services are often developed in response to new scientific needs. Resources that have been added over the past year have been added to a separate listing to help publicize the research tools that are available.
Animal Models
Genetically Modified Mouse Models (Core Facility)
Comparative Pathology/Diagnostic Laboratory (Core Facility)
Humanized Mouse (Limited Access)
Mouse Neurobehavior (Core Facility)
Oncology Precision Therapeutics and Imaging (Core Facility)
Small Animal Radiation Research Platform (Core Facility)
Biorepositories and Assays
Biomarkers at HICCC (Core Facility)
Biomarkers at CTSA (Core Facility)
Center for Advanced Laboratory Medicine (Core Facility)
Tumor Bank (Molecular Pathology Core Facility)
Additional Resources:
- Cells and blood components from healthy donors can be requested from Comprehensive Cell Solutions, part of the New York Blood Center
Flow Cytometry/FACS
HICCC/CCTI: Black Building, Irving Cancer Research Center locations (Core Facility)
Stem Cell Initiative: Black Building location (Core Facility)
Microbiology & Immunology: HHSC Location
Additional Resources
- Cytek Aurora at Human Immune Monitoring Facility
Histology/Pathology
Histology Service in Molecular Pathology (Core Facility)
- Routine and specialized histology services including grossing, embedding, tissue processing, sectioning
- Routine H&E or specialized staining
- Frozen and FFPE tissue
- Experimental immunohistochemistry/ immunofluorescence service
Digital and Computational Pathology Laboratory (Core Facility)
- Acquisition of high resolution images of tissue slides using bright field and fluorescence scanners
Vectra platform at Human Immune Monitoring (Core Facility)
- Quantitative multiplex immunofluorescent tissue imaging
Imaging and Microscopy
Confocal and Specialized Microscopy (Core Facility)
Cryogenic Electron Microscopy (Core Facility)
In vivo Imaging (Limited Access)
Additional Resources
- Zeiss 710 confocal microscope
Microbiome
MRI/PET
Magnetic Resonance Imaging (CUIMC Core Facility)
Magnetic Resonance Imaging (ZMBBI Core Facility)
Positron Emission Tomography (Core Facility)
Proteomics and Metabolomics
Proteomics at HICCC (Core Facility)
Targeted Metabolomics and Lipidomics at CTSA Biomarkers (Core Facility)
Mass Spectrometry, including Mass Spec Imaging, at Morningside (Core Facility)
Sequencing
Next-Generation Sequencing (Core Facility)
Single-cell Analysis (Core Facility)
Additional Resources:
- Collaboration-based NGS projects at the New York Genome Center (Limited Access)
- Note: Sanger sequencing is not provided by cores at Columbia; laboratories use third-party vendors with on-campus pickup services.
Stem Cells
Stem Cell Core (Core Facility)
Mouse embryonic stem (ES) derivation service at Genetically Modified Mouse Models (Core Facility)