The 2018-2019 Heidelberger-Kabat Lecture
“Transposon Molecular Domestication and the Evolution of the Adaptive Immune System”
David G. Schatz, PhD
Waldemar Von Zedtwitz Professor of Immunobiology
Professor of Molecular Biophysics and Biochemistry
Chair of Immunobiology
Wednesday, June 5, 2019
William Black Building
650 West 168th Street, First Floor
Lunch to follow
Dr. David Schatz is professor and chair of the Department of Immunobiology at Yale School of Medicine and professor of molecular biophysics and biochemistry at Yale University. He is a biochemist and molecular biologist with a long-standing interest in the genetic underpinnings of adaptive immunity. Research in his laboratory, which includes about 12 researchers who receive NIH funding, examines the mechanism, regulation, and evolution of V(D)J recombination and somatic hypermutation, reactions that create and refine antibody and T cell receptor genes.
Dr. Schatz earned a BS (summa cum laude) in molecular biochemistry and biophysics from Yale University, a BA in philosophy and politics from Oxford University as a Rhodes Scholar, and a PhD in biology from Massachusetts Institute of Technology and the Whitehead Institute for Biomedical Research based on research he performed in the laboratory of Dr. David Baltimore. This research resulted in the discovery of the recombination activating genes (RAG1 and RAG2) of central importance for the development and function of the immune system.
Dr. Schatz has co-authored over 160 papers and reviews, many in top journals, and has trained approximately 50 graduate students and postdocs. He received the Becton-Dickinson Biosciences Investigator Award from the American Association of Immunology in recognition of his "outstanding contributions to the field of Immunology" and has served as an editor of Immunity and as chair of an NIH study section (CMI-A). Dr. Schatz is an elected member of the American Academy of Arts and Sciences, a fellow of the American Association for the Advancement of Science, and a member of the National Academy of Sciences.